Androgen Insensitivity Syndrome (AIS) is a fascinating and complex condition that challenges our understanding of genetics, gender, and biology. This article delves into the intricate relationship between genes and phenotype, specifically in the context of AIS. What is Androgen Insensitivity Syndrome? Androgen Insensitivity Syndrome is a genetic disorder affecting the development of male sexual characteristics....
Introduction to Androgen Insensitivity Syndrome Androgen Insensitivity Syndrome (AIS) is a rare genetic disorder affecting sexual development. It occurs in individuals who are genetically male (having XY chromosomes) but whose bodies are unable to respond properly to male sex hormones (androgens). This condition leads to the development of female physical characteristics and, in most cases,...
Understanding Androgen Insensitivity Syndrome Biological Basis Genetic Origin: AIS is caused by mutations in the androgen receptor gene, leading to varying degrees of resistance to androgens (male sex hormones) in a genetically male individual (XY chromosome). Types of AIS: The syndrome is classified into complete (CAIS), partial (PAIS), and mild (MAIS) forms, depending on the...
Introduction Androgen Insensitivity Syndrome (AIS) is a genetic condition affecting the body’s responsiveness to androgens, the male sex hormones. These hormones are crucial for typical male sexual development, and AIS can lead to varying degrees of male sexual characteristics in individuals who are genetically male (having one X and one Y chromosome). Genetic Causes of...