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Orexin Archives - Dr. Zaar

January 8, 2024

Case Study: Patient: Sarah, a 25-year-old woman from Karachi, Pakistan, presented with a two-year history of progressive weight gain, excessive daytime sleepiness, and difficulty staying awake during the day. Sarah reported uncontrolled hunger cravings leading to overeating, poor quality sleep with frequent early morning awakenings, and a constant feeling of fatigue despite getting 8-10 hours...

January 8, 2024

Case Study: Sarah, a 35-year-old marketing executive, has always struggled with maintaining a healthy weight. Despite exercising regularly and following a balanced diet, she battled constant cravings and an insatiable appetite. Her excessive daytime sleepiness and frequent bouts of narcolepsy-like cataplexy added to her frustration. After years of consultations and countless weight-loss programs, Sarah remained...

January 8, 2024

Case Study: From Restless Rhapsody to Harmonic Interlude – Patient: Sarah, a 32-year-old marketing executive, has struggled with chronic insomnia for over five years. Despite excellent sleep hygiene and a healthy lifestyle, she experiences difficulty falling asleep, frequent nighttime awakenings, and daytime fatigue. The relentless “restless rhapsody” of her sleep cycle significantly impacts her work...

January 8, 2024

Case Study: Subject: Orexin, a neuropeptide in the hypothalamus. Objective: To investigate the impact of orexin on ten key hormonal systems, delving into its influence on various physiological processes. Methodology: A comprehensive review of scientific literature focusing on orexin’s interactions with hormones and their downstream effects. Findings: Appetite Regulation: Orexin directly inhibits leptin’s satiety-inducing effect...

January 8, 2024

Case Study: Patient: Sarah, 32-year-old marketing professional Presenting Symptoms: Excessive daytime sleepiness, despite adequate sleep at night. Difficulty concentrating and feeling productive at work. Unexplained weight gain despite maintaining a healthy diet. Increased anxiety and difficulty managing stress. Irregular menstrual cycles and mood swings. Medical History: No previous diagnoses or major medical issues. Family history...

January 8, 2024

Case Study: Sarah, a 32-year-old woman, had always struggled with her weight. Despite a relatively healthy diet and regular exercise, the pounds seemed to cling to her tenaciously. Her frustration became compounded by fatigue, excessive daytime sleepiness, and occasional episodes of cataplexy, where an unexpected laugh would make her knees buckle. Consulting with her doctor...

January 8, 2024

Case Study: Sarah, a 35-year-old marketing executive, has always struggled with unexplained bouts of extreme sleepiness. Despite ample sleep, she experiences frequent cataplexy, sudden muscle weakness triggered by emotions like laughter or surprise. Doctors diagnosed her with narcolepsy, a chronic sleep disorder characterized by excessive daytime sleepiness and cataplexy. Puzzled by the cause, Sarah embarked...

January 8, 2024

Case Study: Patient: Sarah, 32 years old Presenting Complaint: Difficulty conceiving for the past year, irregular menstrual cycles, weight gain Medical History: No chronic health conditions, diagnosed with PCOS at age 25 Investigations: Hormone levels: Elevated LH and insulin, low FSH and estrogen Pelvic ultrasound: Multiple small follicles on ovaries MRI: No evidence of hypothalamic...

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