Case Study: HPL and PCOS in Pregnancy

January 27, 2024by Dr. S. F. Czar0

Case Study: HPL and PCOS in Pregnancy

Patient Profile:

  • Name: Rebecca
  • Age: 28
  • Gestational Age: 20 weeks
  • Medical History: Rebecca was diagnosed with PCOS in her early twenties and had been managing the condition with lifestyle modifications and metformin before pregnancy.

Clinical Presentation:

  • Symptoms: During her second trimester of pregnancy, Rebecca experienced a resurgence of PCOS-related symptoms, including irregular menstrual cycles, hirsutism, and acne.

Diagnostic Workup:

Given Rebecca’s history of PCOS and her symptoms during pregnancy, her healthcare provider conducted a comprehensive evaluation:

  • Hormonal Assessment: Hormonal tests were performed, including measurements of insulin levels, androgens, and HPL.
  • Ultrasound: Ovarian ultrasound was conducted to assess any changes in ovarian morphology during pregnancy.


Based on the diagnostic workup, Rebecca was diagnosed with a recurrence of PCOS symptoms during pregnancy.


This case study highlights the role of HPL in the context of PCOS during pregnancy:

1. Clinical Presentation:

  • Rebecca’s resurgence of PCOS-related symptoms during pregnancy indicated that hormonal changes associated with pregnancy might affect PCOS.

2. Hormonal Monitoring:

  • Comprehensive hormonal assessments, including HPL levels, were essential in diagnosing the recurrence of PCOS symptoms.

3. Treatment Adjustments:

  • Rebecca’s healthcare provider made adjustments to her treatment plan, considering the presence of HPL during pregnancy, to address the resurgence of PCOS symptoms.

4. Maternal and Fetal Health:

  • Close monitoring of both Rebecca’s health and fetal well-being was crucial to prevent complications related to PCOS during pregnancy.


  • Rebecca’s healthcare team successfully managed the recurrence of her PCOS symptoms during pregnancy through adjustments to her treatment plan.
  • Regular monitoring ensured that her hormonal levels remained within the desired range, reducing the risk of complications for both her and her baby.


Rebecca’s case illustrates the significance of recognizing the potential impact of HPL on PCOS during pregnancy. By understanding the hormonal complexities involved, healthcare providers can tailor treatment approaches, monitor patients effectively, and offer insights into the management of PCOS symptoms during pregnancy. This case also underscores the importance of multidisciplinary care and patient education to optimize the health and well-being of women with PCOS during this unique life stage

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