Case Study: The Prolactin Phantom and the Unexpected Dancer

Case Study: The Prolactin Phantom and the Unexpected Dancer

Patient: Maria, a 45-year-old woman, seeking medical advice for persistent headaches and irregular periods.

Medical History: No prior surgeries or known pituitary issues. Family history of migraines.

Presentation: Physical examination unremarkable. Blood tests reveal elevated prolactin levels, while other pituitary hormones (thyroid, cortisol) are normal.

Investigation: MRI scan confirms an empty sella turcica, with the pituitary gland flattened but appearing structurally intact. Further tests rule out pituitary tumors or other potential prolactin-raising conditions.

Diagnosis: Empty sella syndrome with likely prolactin elevation due to cerebrospinal fluid mimicking the pituitary’s signals.

Treatment: Cabergoline medication prescribed to lower prolactin levels. Regular monitoring of hormonal balance and headaches.

Outcome: Over 3 months, Maria’s headaches subsided and menstrual cycles returned to normal. Prolactin levels stabilized within the desired range.

The Unexpected Dancer: While Maria presented with typical empty sella symptoms, the prolactin elevation was a surprising twist. The mimicry from the cerebrospinal fluid, an uncommon contributor to prolactin imbalance in empty sella, added an unexpected layer to her case.

Lessons Learned:

• Empty sella syndrome can present with diverse symptoms, not just hormonal imbalances.
• Prolactin elevation in empty sella may not always directly involve the pituitary gland.
• Careful differential diagnosis and tailored treatment are crucial for optimal outcomes.

The Empty Sella Enigma: Maria’s case highlights the enigmatic nature of empty sella syndrome. It demonstrates how the prolactin phantom can play unexpected roles, requiring the medical detective to interpret the clues and orchestrate a successful therapy.

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