case Study: hCG in Pregnancy-Related Hyperthyroidism

January 27, 2024by Dr. S. F. Czar0

Case Study: hCG in Pregnancy-Related Hyperthyroidism

Patient Profile:

  • Name: Emily
  • Age: 28
  • Gender: Female
  • Medical History: Emily is in her first trimester of pregnancy and has a history of Graves’ disease, an autoimmune hyperthyroid condition.
  • Presenting Complaint: Emily experiences palpitations, excessive sweating, and anxiety during pregnancy.

Clinical Presentation:

  • Symptoms During Pregnancy: Emily’s symptoms of palpitations, excessive sweating, and anxiety raise concern, especially given her history of Graves’ disease.

Diagnostic Workup:

Given Emily’s presentation and medical history, her healthcare provider conducts a comprehensive evaluation:

  • Thyroid Function Tests: Blood tests reveal elevated thyroid hormone levels (T4 and T3) and low TSH levels, consistent with hyperthyroidism.
  • hCG Levels: hCG levels are measured as part of the evaluation to assess whether pregnancy-related hCG elevation is contributing to her hyperthyroidism.


Based on her clinical presentation and diagnostic findings, Emily is diagnosed with pregnancy-related hyperthyroidism, exacerbated by elevated hCG levels.


This case study highlights the role of hCG in pregnancy-related hyperthyroidism:

1. Clinical Presentation:

  • Emily’s symptoms of hyperthyroidism during pregnancy prompt further evaluation due to her history of Graves’ disease.

2. Thyroid Function Tests:

  • Emily’s thyroid function tests confirm the diagnosis of hyperthyroidism, characterized by elevated thyroid hormone levels and low TSH levels.

3. hCG Levels:

  • The assessment of hCG levels reveals that her pregnancy hormones are contributing to the exacerbation of her hyperthyroidism.

4. Treatment Considerations:

  • Emily’s healthcare provider adjusts her treatment plan to manage both her pregnancy and hyperthyroidism, considering the potential impact of hCG on her thyroid function.

5. Monitoring and Support:

  • Emily receives regular monitoring of her thyroid function and hCG levels throughout her pregnancy to ensure that her hyperthyroidism is well-managed.


Emily’s case exemplifies the complex interplay between hCG and hyperthyroidism, especially during pregnancy. Recognizing the influence of hCG on thyroid function is essential for providing appropriate and personalized care to individuals like Emily, ensuring the well-being of both the mother and the developing fetus during pregnancy-related hormonal imbalances.

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