Case Study: Calcitonin in Osteoporosis Management

February 2, 2024by Mian Marssad0

Patient Profile:

  • Patient’s Name: Mary
  • Age: 68 years
  • Gender: Female
  • Chief Complaint: Persistent back pain and a recent vertebral fracture

Medical History:

Mary is a 68-year-old woman who has been experiencing persistent back pain for several months. Her pain worsened after a minor fall, leading to a diagnosis of a vertebral fracture. Mary’s medical history includes postmenopausal osteoporosis, for which she had previously tried bisphosphonate therapy. However, she had to discontinue it due to gastrointestinal side effects.

Clinical Assessment:

Upon examination and bone density assessment, Mary’s healthcare provider confirms her diagnosis of osteoporosis. Her bone density scans reveal a significant reduction in bone mass, particularly in the lumbar spine and hip. Blood tests indicate that her calcidiol (25-hydroxyvitamin D) levels are within the recommended range, but her pain and fracture risk warrant further intervention.

Treatment Plan:

Mary’s healthcare provider formulates a treatment plan that includes calcitonin therapy:

  • Calcitonin Nasal Spray: Mary is prescribed a calcitonin nasal spray as part of her osteoporosis management. The nasal spray is administered daily, and she receives instructions on its proper use.
  • Calcium and Vitamin D Supplementation: To support her bone health, Mary is advised to continue taking calcium and vitamin D supplements. These supplements help ensure adequate calcium intake and absorption.
  • Pain Management: Mary is prescribed pain medications to manage her back pain. The goal is to improve her comfort and mobility while the calcitonin therapy addresses the underlying bone issues.
  • Lifestyle Modifications: Mary is encouraged to engage in weight-bearing exercises, such as walking and gentle strength training, to help strengthen her bones and improve balance. Fall prevention strategies are also discussed to reduce the risk of future fractures.

Progress and Results:

Over the course of several months, Mary undergoes regular follow-ups to monitor her progress. The following outcomes are observed:

  • Pain Relief: Mary reports a gradual reduction in back pain, making it easier for her to perform daily activities.
  • Fracture Risk Reduction: Mary’s follow-up bone density scans show stabilization of bone loss in the spine and hip. The risk of additional vertebral fractures is significantly reduced.
  • Improved Mobility: With the combination of calcitonin therapy, pain management, and exercises, Mary experiences improved mobility and a better quality of life.
  • Adherence: Mary adheres well to her treatment plan, including the daily use of the calcitonin nasal spray.

Conclusion:

Mary’s case highlights the valuable role of calcitonin in osteoporosis management, particularly in individuals who cannot tolerate or have contraindications to other osteoporosis medications. While calcitonin is not typically a first-line treatment, it can provide pain relief, reduce fracture risk, and enhance the overall well-being of patients like Mary who are dealing with the challenges of osteoporosis. This case underscores the importance of personalized treatment plans tailored to individual patient needs and circumstances to optimize outcomes and minimize the impact of osteoporosis on their lives.

Calcitonin and Hypercalcemia: A Key Regulator of Calcium Homeostasis”

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