Case Study: Diagnostic Role of hCG in Ectopic Pregnancy

January 27, 2024by Dr. S. F. Czar0

Case Study: Diagnostic Role of hCG in Ectopic Pregnancy

Patient Profile:

  • Name: Sarah
  • Age: 28
  • Gender: Female
  • Medical History: Sarah has a history of irregular menstrual cycles and had been actively trying to conceive for several months.
  • Presenting Complaint: Sarah experiences sudden, severe lower abdominal pain and vaginal bleeding.

Clinical Presentation:

  • Physical Examination: Sarah appears distressed and is in significant pain. On examination, her vital signs are stable, but tenderness is noted in her lower abdomen.
  • Initial Laboratory Tests: Sarah’s initial hCG level is measured and found to be elevated.

Diagnostic Workup:

Given Sarah’s symptoms and elevated hCG level, further investigations are conducted:

  • Transvaginal Ultrasound: A transvaginal ultrasound is performed to visualize the pregnancy. The ultrasound confirms that the gestational sac is located outside the uterus, in the right fallopian tube, consistent with an ectopic pregnancy.


Based on the clinical presentation, elevated hCG levels, and transvaginal ultrasound findings, Sarah is diagnosed with an ectopic pregnancy.


This case study illustrates the diagnostic significance of hCG in ectopic pregnancy:

1. Elevated hCG Levels:

  • The elevated hCG levels in Sarah’s blood sample served as a critical clue, prompting further investigations into her condition.

2. Transvaginal Ultrasound:

  • Transvaginal ultrasound is a valuable tool for visualizing the pregnancy and its location. In Sarah’s case, it confirmed the ectopic pregnancy by showing the gestational sac outside the uterus.

3. Importance of Early Diagnosis:

  • Sarah’s prompt presentation and diagnostic workup allowed for early detection of the ectopic pregnancy. Early diagnosis is crucial to prevent complications, such as fallopian tube rupture.

4. Treatment:

  • Following the diagnosis, Sarah underwent minimally invasive laparoscopic surgery to remove the ectopic pregnancy from her fallopian tube. This intervention helped preserve her fertility and mitigate potential complications.


Sarah’s case highlights the pivotal role of hCG in diagnosing ectopic pregnancy. Elevated hCG levels, coupled with imaging techniques like transvaginal ultrasound, enable healthcare providers to identify and manage ectopic pregnancies in a timely manner. Understanding the diagnostic significance of hCG in ectopic pregnancy is essential for providing appropriate care and preventing life-threatening complications in affected individuals.

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