Calcitriol and its Biological Functions: Calcitriol, or 1,25-dihydroxyvitamin D3, is the hormonally active form of vitamin D. Traditionally known for its role in calcium and bone metabolism, recent studies have expanded its potential functions to include modulation of insulin secretion and sensitivity. Pathophysiology of Diabetes Mellitus: Type 1 Diabetes: T1D involves autoimmune-mediated destruction of … Continue reading The Influence of Calcitriol on Insulin Secretion and Resistance